How to change the origin of waypoint in UAV Package Delivery

I want the UAV to travel from [-20,1] to [-88.1056,74.2231] while avoiding obstacles (oaMission) as seen in figure below. To do this, I modified the first 2 waypoints of oaMission as seen in the image below. I also updated the initial translation from the Simulation 3D UAV Vehicle  as seen in image below When Simulink was running at the first 3 seconds, the unreal engine started at the assigned starting point [-20,1]. However, the scene suddenly went back to the original starting point [-185.82188,-104.91064,0].